HIELSCHER UP400ST Powerful Ultrasonicator

The UP400St is suitable for various applications such as homogenization, emulsification, dispersion, deagglomeration and wet milling (particle size reduction), cell disruption and disintegration, extraction, degassing and sonochemistry.

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HIELSCHER UP400ST Powerful Ultrasonicator

With the Hielscher UP400St Powerful Ultrasonicator (400W, 24kHz), the Hielscher series of digital ultrasonic devices is extended with a powerful 400 watt ultrasound.

The new UP400St is the successor to the UP400S, one of Hielscher’s most popular laboratory systems.

Its high ultrasound power and robustness make the UP400St perfectly suited for use in demanding environments.

Equipped with a color touchscreen for easy control, integrated LEDs for sample illumination, plug-in temperature sensor, integrated SD card for automatic data logging as well as many other features, the UP400St convinces with its ease of use and reliability.

The UP400St is ideal for efficient and accurate sonication of large samples.

As our most powerful laboratory device, the UP400St is suitable for various applications such as:

homogenisation, emulsification, dispersion, deagglomeration and wet milling (particle size reduction), cell disruption and disintegration, extraction, degassing, as well as sonochemical processes.

With sonotrodes ranging in diameter from 3 to 40 mm, the device is suitable for sonication of sample volumes from 5 to 4000 ml.

In combination with a flow cell, approximately 10 to 50 liters per hour can be sonicated.

When used for sample preparation, the UP400St is primarily used for larger volumes.

It is suitable for the development of ultrasonic applications in the laboratory, but also in benchtop optimization, as well as for small quantity production.

The device’s functions and various accessories allow for different applications and the coverage of very wide parameter settings.

The UP400St convinces as a powerful and reliable ultrasonic homogenizer:

It can run continuously 24h/7d at full load and is good for processing up to 400L/h.

In general, the UP400St is used for sonication of volumes from 5.0 to 4000 mL.

Due to its robustness and its ability to operate 24/7, the UP400St can also be used for smaller quantity production.

For production processes, sonication is mainly carried out in a continuous flow system with a flow cell and a sonotrode with sealing for the flow cell reactor.

In combination with the FC22K flow cell, the material can be sonicated in continuous flow mode, e.g. at a flow rate of 20 to 200 mL. per minute (final capacity depends on the application).

The stainless steel flow cell is pressurizable up to 5 barg and is equipped with a cooling jacket.

In this way, in-line ultrasonic processes can be simulated at minimum scale.